It is possible that the difference observed in asthma attack patients and remission patients were due to different treatments, however, there were no statistical significances between patients in the remission group with or without treatment in serum mTOR, Th17, Treg, IL-17, TGF-β, IL-10, IL-4, and IFN-γ (Supplemental Table 1), which indicates that the differences observed between asthma attack patients and asthma remission patients were not attributed to steroid or β2-adrenergic receptor agonists treaments. This evidence concerns the gene IL4 and asthma.