ApoE-/-/DKK3+/+ chimeric mice transplanted with DKK3-/- bone marrow showed comparable neointimal hyperplasia to ApoE-/-/DKK3+/+ mice with wild-type bone marrow 3 weeks after femoral artery wire injury (Figure 4B), indicating that DKK3 expression in hematopoietic-derived cells does not contribute to protection from atherosclerosis and neointima formation postinjury. Here, DKK3 is linked to atherosclerosis.