We also showed that in HGPS patients' nuclei, PML‐NBs contained, in addition to progerin, two nuclear envelope proteins: lamin B and emerin; conventional PML protein components were observed as follows: SP100, HP1, DAXX, CBP, and ATRX, while lamin A/C was absent. The gene discussed is EMD; the disease is Hutchinson-Gilford progeria syndrome.