TP53 and acute myeloid leukemia: The DS3032b compound is an inhibitor of the P53-MDM2 interaction developed by Daiichi Sankyo that has reached the clinical assessment in 2013, and it is now under evaluation in three studies in patients affected by different types of tumors including AML, ALL, CML, MDS (id: NCT02319369), advanced solid tumors or lymphomas (id: NCT01877382), and relapsed/refractory multiple myeloma patients (id: NCT02579824).