GPC3 and acute respiratory distress syndrome: In summary, we have gained following based on our results: firstly, both SNS and PNS activity were markedly elevated in rabbits with HCl-induced ALI and the disturbance of ANS homeostasis was attributed to a predominance of SNS activity; Secondly, all three treatment methods including VNS, THA and SGB could effectively regulate the disequilibrium of ANS, and improve pulmonary function; thirdly, SGB treatment was the most effective approach in regulating ANS balance.