SCARB1 and Alzheimer disease: However, theoretically, any SNPs in genes involved in the absorption (SR-B1, NPC1L1, CD36) uptake (APOB, APOE, LPL, SR-B1), hepatic transport (TTPA), or egress (ABCA1, ABCG1) of alpha-tocopherol level modulation are candidates for affecting the therapeutic response of vitamin E for AD treatment.