The MAPK, including c‐Jun NH2‐terminal kinase (JNK), p38 MAPK, and extracellular signal‐regulated kinase (ERK), regulates various cancer‐related cellular activities, including promoting survival, proliferation, angiogenesis, as well as suppressing apoptosis (Kim and Choi, 2015). The gene discussed is MAPK8; the disease is cancer.