This is a molecular alteration which might be targetable by mesenchymal-to-epithelial transition factor tyrosine kinase inhibitors [20].These findings with ours are of interest because PSCGCC seems different from NSCLC in their PD-L1 expression and gene expression profile, this might be a help for patient selection for PD-L1 testing and molecular testing. Here, CD274 is linked to non-small cell lung carcinoma.