The dependency of this site is variable considering the two cell lines we tested, but nevertheless NF-κB plays a key role in VEGF-C regulation, as suggested in another cancer type.32 As these cell lines came from two different patients, our results highlight the inter-patient variability in VEGF-C expression and regulation, stressing out the importance of implementing personalized diagnosis and treatment strategies. The gene discussed is NFKB1; the disease is cancer.