ALDH1A1 and familial pancreatic carcinoma: Along with the findings mentioned above, since pancreatic cancer stem-like cells are poorly differentiated in general and proliferate rapidly, we tried to investigate the contribution of NRF2 to pancreatic oncogenesis by monitoring the expression of ALDH1A1 and ALDH3A1 and measuring the anticancer drug sensitivities under the condition of siRNA-induced NRF2 depletion.