HDAC1 and ovarian carcinoma: The in vitro analysis of different HDACs isoforms using siRNA (small interfering RNA) against HDAC1, HDAC2 and HDAC3 on several ovarian carcinoma cells (SKOV3, OVCAR3, IGROV-1, ES-2, TOV112D, A2780 and A2780/CDDP) showed that knockdown of HDAC1 inhibits proliferation and tumorigenicity, while knockdown of HDAC3 reduces cell migration with an increase in E-cadherin.