NOS1 and intrahepatic cholangiocarcinoma: Of interest, increased ICC numbers were observed in transplanted nNOS−/− mice both in the distal (77±3; n=3) and proximal colon (130±11; n=3) compared to sham-operated nNOS−/− distal (P=0.0006, Student’s t-test; Fig. 6e) and proximal (P=0.0135, Student’s t-test; Fig. 6f) colon, respectively.