BCL2 and neoplasm: In this proof‐of‐concept study, the α‐helical PPI of Mcl‐1 and Noxa, members of the apoptosis‐regulating Bcl‐2 family of proteins, was employed as an example.14 Anti‐apoptotic proteins (e.g., Bcl‐2, Bcl‐xL, and Mcl‐1) are often overexpressed in cancer, contributing to the development of the tumor and resistance to current therapies.15