In addition, in mice, many of these cytokines and chemokines such as macrophage inflammatory protein-2 (MIP-2), mouse keratinocyte factor (mKC), and macrophage chemoattractant protein-1 (MCP-1) have their own receptors i.e. CXC chemokine receptor 1 (CXCR1), CXC chemokine receptor 2 (CXCR2), and C-C chemokine receptor 2 (CCR2), respectively, all of which have been implicated in specific liver diseases [25-30]. Here, CXCR2 is linked to liver disorder.