KIRREL3 and Intellectual disability: Point mutations, copy number variations, and deletions in Kirrel3 have been repeatedly identified in patients with intellectual disability (Bhalla et al., 2008; Kaminsky et al., 2011; Talkowski et al., 2012), autism spectrum disorders (Ben-David and Shifman, 2012; Iossifov et al., 2012; Michaelson et al., 2012; Neale et al., 2012; Talkowski et al., 2012; Cheng et al., 2013; De Rubeis et al., 2014), and Jacobsen’s syndrome (Guerin et al., 2012).