While the 138 kb duplication in our study, mapped to the 3′ end of DPP10, might be a benign polymorphism, our findings do not exclude the possibility that other genomic variants involving DPP10 can still have functional impact on neuronal potassium channel gating, and hence contribute to the pathogenesis of ASD and other neurodevelopmental disorders. Here, KCNA3 is linked to neurodevelopmental disorder.