Furthermore, in human vascular ECs, other genes related to ECM synthesis and maintenance of ECM integrity, such as elastin (ELN), collagen type 4 alpha 1 (COL4A1), phosphatase and tensin homolo (PTEN), and vascular endothelial growth factor A (VEGFA), were recently identified as targets of miR-29c and are significantly elevated in the sera of AAA patients (Licholai et al., 2016). The gene discussed is PTEN; the disease is triple-A syndrome.