Johan, two years old with Kawasaki syndrome, is being cared for in the pediatric ward. You are sure about the diagnosis, but Johan has not responded to standard treatment with intravenous immunoglobulin (IVIG) in combination with acetylsalicylic acid (ASA). 48 hours after IVIG, Johan still has a fever of 39°C, rising C-reactive protein at 211 mg/L, and increased absolute neutrophil count at 18×109/L. You want to intensify the treatment and are considering what alternative you ought to choose. The gene discussed is CRP; the disease is Kawasaki disease.