The medium levels of plasma UCHL1 was 261.2 ng/ml (interquartile range 131.8–383.9) and 647.8 ng/ml (interquartile range 401.8–875.3) for healthy donors and patients with CHC (p < 0.0001), respectively, as found by dot plot analysis (Fig. 4C). The gene discussed is UCHL1; the disease is cryohydrocytosis.