APOA1 and rheumatoid arthritis: In the multivariable model, smoking and elevated ApoB/ApoA1 ratio remained significantly associated with increased risk for subsequent RA (OR = 1.82 (1.37–2.41) and OR = 1.36 (1.03–1.80), respectively) in women (Table 3), which was unchanged after adjustment for educational level (data not shown).