These decreases were largely attributed to the absence of Ly6C+CCR2+ inflammatory monocytes, and Ly6C+CCR2- inflammatory monocyte-derived cells, but also extended to other cell types (Fig 7C), confirming that during the inflammatory response at a dermal site of infection, CCR2+ monocytes undergo maturation and populate these cellular niches. The gene discussed is CCR2; the disease is infection.