Therefore, Geldanamycin showed a more marked protection than oseltamivir (Figure 1) in survival rate, weight recover etc. In addition, GA treatment significantly inhibited the production of multiple proinflammatory cytokine and chemokines (Figure 4) and suppressed the accumulation of activated (CD69+) macrophages/monocytes and NK cells in the infected lung 24–48 h post-infection (Figure 5). The gene discussed is CD69; the disease is infection.