LMNA and metabolic syndrome: Other variants linked to FPLD2 (Figure 4B; Burke and Stewart, 2002) or reported in metabolic syndrome patients (MetS; Figure 4B) are also somewhat clustered, affecting residues R439, G465, R482, K486, H506, or K515 on the Ig-fold surface (Chirico et al., 2014; Scharner et al., 2014).