CAMK2A and breast cancer: However, bacopa and bacoside A which enhance CaMK2A phosphorylation, are also demonstrated to exert excellent cytotoxic effects on breast cancer cells, in hepatocarcinogenesis etc. (Janani et al., 2010; Prakash et al., 2011; Nandagaon and Kulkarni, 2013; Yadav and Reddy, 2013; Jose et al., 2014; Patil et al., 2014; Mallick et al., 2015).