Although, we observed some variability in NLRP12 protein size at 95 kDa and 70 kDa, the constitutive level of NLRP12 was low to non-detectable in LNCaP and LNCaP-Ln3 cell lines as compared to aggressive prostate cancer cell lines, and corresponds with the expression profile in archival human prostate tissues. The gene discussed is NLRP12; the disease is Familial prostate cancer.