Ablation of MyD88 impairs intestinal tumor formation induced by the administration of the carcinogen azoxymethane and the spontaneous tumor development in mice with heterozygous mutation in the adenomatous polyposis coli gene, as well as diethylnitrosamine-induced hepatocarcinogenesis associated with a reduced IL-6 production [8,9]. The gene discussed is MYD88; the disease is neoplasm.