MLKL and systemic inflammatory response syndrome: We thank Stephanie Kourula and Divert Tatyana for their help with the TNF-induced SIRS model, Ria Roelandt for providing recombinant kinase material and Jolien Bridelance for providing the L929sAhFas MLKL-/- inducible mMLKL-Flag and mMLKL-S345D-Flag cells.