Importantly, stratifying breast cancer patients by dual c-Abl and wild-type p53 expression trended to be a more powerful prognostic indicator of patient survival as compared to singular stratification of c-Abl.11 These findings suggest that p53 expression and its mutational status could be an important contributor to the functional output of c-Abl across different breast cancer subtypes and contexts. This evidence concerns the gene TP53 and breast carcinoma.