VEGFA and diabetes mellitus: Recent studies have shown that abundant VEGF derived from retinal ganglion cells 40, 41, 42, Müller cells 43, 44, 45 and RPE 46, 47 can stimulate endothelial cells and the resultant promotion of retinal angiogenesis in the OIR model, diabetes mellitus model or experimental choroidal neovascularization, respectively.