Especially, it has been reported that basigin may promote angiogenic process not only through its protease‐inducing function by up‐regulating matrix metalloproteinase (MMPs) secretion 11, 12, but also directly by its ability to increase soluble forms of VEGF and VEGFR2 in tumour cells and endothelial cells 13, 14, 15. This evidence concerns the gene BSG and neoplasm.