That acute physical stress induces hyperglycemia and that the second messengers involved in ABA signaling in granulocytes, cAMP and cADPR, played a role in the signaling leading to glucose-induced insulin secretion (30, 31) suggested to explore the possible role of ABA in the arguably most important aspect of mammalian nutrient disposal, i.e., insulin release (13). Here, INS is linked to Hyperglycemia.