Several proteins, including CD45, CD45R0, CD48, CD137, IL-17 receptor (R) A and B, αL integrin, and some of the Fc receptors, are increased or decreased on circulating eosinophils in asthma compared to normal, non-allergic healthy individuals (Table 1) (8, 19). This evidence concerns the gene TNFRSF9 and asthma.