Disabled autophagy has been linked to multiple distinct pathologies including inflammatory diseases such as pancreatitis.9,10,11 Thus, depletion of pancreatic Atg7 or Atg5 (which both are essential for the autophagic process) can induce acinar cell death, thereby triggering acute pancreatitis (AP) and later chronic pancreatitis (CP).10,12,13. Here, ATG7 is linked to pancreatitis.