SOD3 and Friedreich ataxia: Besides, neuroprotective effects have been noticed for the SOD3 secreted by mesenchymal stem cells on cerebellar cells in vitro (9), and higher levels of CAT have been observed in a transgenic mouse model (YG8) for Friedreich’s ataxia (FRDA) (10), highlighting the significance of these enzymes in counteracting neurodegenerative processes.