However, cMyBP-C−/− pups had higher HW to BW ratios than their time-matched WT littermates at the remaining time points of PND2 (%, 0.61 ±0.01 vs. 0.57 ±0.01, ±SE, respectively) and PND9 (%, 0.64 ±0.02 vs. 0.51 ±0.01, respectively, ±SE, P < 0.001; Figure 3, bottom), suggesting that gross cardiac hypertrophy exists at the organ level starting at PND2 in the homozygote null animals (See Supplementary Table 4 for numbers of mice per genotype/day point). The gene discussed is MYBPC3; the disease is cardiac hypertrophy.