It is well-documented that tumor necrosis factor alpha (TNFα), a pro-inflammatory cytokine, plays a significant role in the pathogenesis of chronic airway inflammatory diseases such as allergic asthma (Thomas, 2001; Howarth et al., 2005; Berry et al., 2006; Heffler et al., 2007; Brightling et al., 2008). The gene discussed is TNF; the disease is allergic asthma.