They found that the prevalence of DM was higher in the non-FH group, reaching 18.7% compared with 3.9% in the FH patients with a defective allele at LDLR and 7.9% in FH patients with a null mutation at LDLR (Table 1) (Vohl et al., 1997). The gene discussed is LDLR; the disease is diabetes mellitus.