EGF and cancer: Numerous mitogenic and pro-angiogenic factors, such as transforming growth factor beta (TGF-β), fibroblast growth factor (FGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF)-like growth factors, endostatin etc., were found in the wound fluids which explains the stimulation of cancer cell proliferation and neoangiogenesis during post-surgery wound healing period (Maniwa et al., 1998; Abramovitch et al., 1999; Wu et al., 2003).