Among five eicosanoid metabolites (LTE4, PGF2α, TXB2, 15-HETE, and eoxin C4), the urinary 15-HETE level was significantly associated with the ABCC4 −1508A>G polymorphism; asthma patients carrying the −1508G allele showed a significantly higher level than that of noncarriers (332 ± 99.31 versus 271.91 ± 89.87 pmol/mg creatinine [pmol/mg Cr], P = 0.032; Figure 1(a)). The gene discussed is ABCC4; the disease is asthma.