Besides, correlation analysis exhibited that DACH1 and CD44 behaved completely differently in the correlations with FN1, VIM, YBX1, FOXA1, EGFR and MKI67. Importantly, DACH1 serves as a protective factor, while CD44 is an unfavorable element for the prognosis of breast cancer patients. The gene discussed is EGFR; the disease is breast cancer.