RAC2 and infection: Additionally, we found that zebrafish with neutrophils harboring a neutrophil-specific dominant negative Rac2 D57N mutation, a model for leukocyte adhesion deficiency (LAD), have impaired neutrophil recruitment to localized sites of infection [28] and are also more susceptible to infection with WT S. iniae [27], but not capsule deficient cpsA insertion mutants.