The results showed that Bmi-1 was significantly associated with tumor size (n = 7, OR = 1.79, 95% CI = 1.19–2.71, P = .005, fixed effect), poor differentiation (OR = 1.61, 95% CI = 1.11–2.33, P = .011, fixed effect), and distant metastasis (n = 4, OR = 4.69, 95% CI = 1.52–14.41, P = .007, fixed effect). This evidence concerns the gene BMI1 and neoplasm.