As shown in Table 1, Alanine aminotransferase (ALT), Aspartate transaminase (AST) and Globuline (GLOB) levels are significantly higher in patients with chronic liver diseases including CHB, LC and HCC compared with HCs, while albumin (ALB) is decreased in the patient groups, which indicates a typical liver damage in the patient groups. This evidence concerns the gene B3GALNT1 and laryngotracheoesophageal cleft.