Furthermore, analyses on patient and tumor characteristics showed that node-positive patients diagnosed by SLNB significantly differed from patients in the UGLNB group; the UGLNB group was older, was more often diagnosed in the period 2008–2011, had a larger tumor, had a poorly differentiated tumor, was more likely to have a negative hormone receptor status, had a multifocal tumor, had undergone a mastectomy, and was less likely to receive adjuvant radiation therapy or systemic therapy. This evidence concerns the gene NR4A1 and neoplasm.