Co-IP to test the combination between GST- RKRKRKKSRYIVLS and VEGFR-1: in a similar way, GST-RKRKRKKSRYIVLS could combined to VEGFR-1 (Fig. 4G,H), indicating that these two peptides could bind to VEGFR-1 and subsequently exert its biological effect on tumor cells. This evidence concerns the gene FLT1 and neoplasm.