CD300LF and Sepsis: To clarify the functions of CD300f−/− mast cells in the defense against sepsis, we used CLP in mast cell-deficient (KitW-sh/W-sh) mice reconstituted intraperitoneally with WT or CD300f−/− BMMCs, with the two types of mice having equivalent numbers of peritoneal mast cells (Supplementary Fig. S6a,b).