MAP2 and Alzheimer disease: A trend toward a decrease was found in MAP2 expression in the CA3 (Fig. 4c and d; one-way ANOVA, post-hoc t test, p = 0.09), the DG (Fig. 4c and d; two-tailed Student’s t test, p = 0.0416) and the parietal cortex (Fig. 4c and d; one-way ANOVA, post-hoc t test, p = 0.0392) in the 3 × Tg-AD-vh compared to WT mice.