Vascular Endothelial Growth Factors (VEGFs) are a family of secreted proteins that regulate many aspects of vascular and lymphatic biology including vasculogenesis (de novo formation of the vascular system), angiogenesis (formation of new capillaries e.g. in response to hypoxia), lymphangiogenesis (de novo formation of the lymphatic system) and arteriogenesis (formation of new arteries e.g. following ischemia). This evidence concerns the gene VEGFA and ischemia.