FGF2 and osteoporosis: To determine whether FGF-2 can be used as a genetic marker to predict the risk of osteoporosis in middle-aged and elderly people, the relationship between FGF-2 haplotypes and bone mass was explored, and the distribution of FGF-2 gene polymorphism and its haplotypes in osteoporosis patients and normal bone mass people were analyzed in middle-aged and senior Zhuang ethnic people in Guangxi, a multi-ethnic region of China.