MMP3 and neoplasm: We have shown that the lncRNA JHDM1D-AS1 is upregulated in response to nutrient starvation and that the subsequent increase in solid pancreatic tumor growth is associated with upregulation of genes for several proangiogenic factors, such as HGF and FGF1, and proinflammatory factors, such as MMP3, MMP9, S100a8, and S100a9, resulting in tumor progression.