We have previously reported that the mRNAs for nutrient starvation-responsive genes, including JHDM1D, the sense gene of JHDM1D-AS1 that is upregulated under nutrient starvation in vitro, were also upregulated in vivo in avascular tumor tissues (11, 12) To investigate whether RNA expression of JHDM1D-AS1 is increased in avascular tumor tissues in vivo, PANC-1 cells were inoculated in scid/scid mice, and tumor samples were obtained on day 0, day 3, day 5, and day 10 (n = 3 per each time point). The gene discussed is KDM7A; the disease is neoplasm.