AFP and hepatocellular carcinoma: Further analysis in HCC patients with AFP negative or other low recurrent risks among the training cohort, we found that HDLPO level retained significant prognostic value in patients who were AFP-negative (P = 0.001), with no satellite lesions (P = 0.046), with complete encapsulated tumors (P = 0.001), and with BCLC stage 0 + A disease (P = 0.004; Fig. 3 a-e).